Audio
Clinical Professionals
Vitamin B6 Toxicity and Other Toxic Sensory Neuropathies
Reviews pyridoxine toxicity and other toxic sensory neuropathies, including Tangier disease, arsenic, thallium, and cisplatin.
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Duration
00:02:33
File size
1.37 MB
Practitioner-Guided Note
Use supplement use, chemotherapy exposure, and environmental or occupational history to identify toxic neuropathy early. A normal motor exam does not exclude a severe sensory neuropathy.
Key Takeaways
Vitamin B6 toxicity causes a pure sensory neuropathy; Supplements can provide neurotoxic pyridoxine doses; Tangier disease can present with peripheral neuropathy and orange tonsils; Arsenic and thallium cause painful toxic neuropathies; Cisplatin can cause coasting sensory neuropathy