Use Transverse Myelitis Treatment and Prognosis to guide the working diagnosis and next step; let the main risk or management issue drive escalation, treatment choice, and follow-up.

If you see that the steroids are failing to turn things around, you should quickly consider escalating to plasma exchange or high-dose intravenous immunoglobulin therapy.; Transverse myelitis typically behaves as an acute to subacute process, hitting its maximum severity or nadir within about 3 weeks of symptom onset.; Long-term recovery pattern can be roughly split into thirds.; Progressive multifocal leukoencephalopathy takes hold when an individual has a severe defect in cell-mediated immunity.; Regardless of what the underlying root cause turns out to be, the absolute standard of care is to treat the acute attack immediately with high-dose intravenous methylprednisolone.