Audio Clinical Professionals

Propranolol, Primidone, and Orthostatic Tremor

Explains the dosing of propranolol for essential tremor, the dosing of primidone for essential tremor, and other medications treat essential tremor in practical Movement Disorder care.

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Duration

00:02:32

File size

0.58 MB

Practitioner-Guided Note

Titrate propranolol and primidone slowly and to tolerance, and complete a medication review and thyroid and pheochromocytoma screen before labeling a symmetric high-frequency tremor as essential. When a patient describes tremor that resolves immediately on walking but returns on standing still, consider orthostatic tremor, as it is frequently misdiagnosed and clonazepam is the preferred first-line treatment.

Key Takeaways

Essential tremor worsens with action or specific postures, tends to be more symmetric, and has a higher frequency and lower amplitude; Clinicians can also consider gabapentin, various benzodiazepines, and acetazolamide-like agents; Tremor that is present at rest but becomes significantly worse with active movement or positioning; We utilize either a thalamotomy or thalamic deep brain stimulation, both of which demonstrate an impressive efficacy rate of up to ninety percent; Your immediate priority should be a thorough review of their medications—paying close attention to things like lithium, tricyclics, neuroleptics, beta-agonists, or anticonvulsants like valproic acid and carbamazepine