Use optic pathway involvement, the rituximab-based regimen, and the classic ganglioglioma pathology to separate lymphoma from the other tumors discussed. The point is to match the treatment path to the correct diagnosis instead of blending three different entities together.

Primary CNS lymphoma often involves the visual pathways; First-line therapy uses high-dose methotrexate with rituximab; Ovarian teratoma is strongly linked to anti-NMDA receptor encephalitis; Ganglioglioma is a firm, circumscribed mass with calcifications and a mural nodule; Hodgkin lymphoma can be associated with granulomatous CNS disease