When akathisia is mistaken for anxiety or agitation, the clinical response to propranolol or dose reduction distinguishes it from primary psychiatric symptoms and prevents unnecessary medication escalation. When myoclonus is the presenting concern, classify it by neurological level and review the medication list systematically, because metabolic and drug-induced myoclonus resolves when the underlying cause is corrected.

More common in women, and individuals are typically younger individuals whose dystonia is highly treatment-resistant, with remissions being exceptionally rare; Takes months to years of steady medication exposure to develop, and the movements are often completely irreversible; Medications that carry the safest profile in this regard are quetiapine and clozapine; First look at discontinuing the offending agent, and then you can trial therapies like propranolol, amantadine, anticholinergics, or clonidine; Intense, distressing sensation of inner restlessness accompanied by an overwhelming urge to move, most commonly developing as a side effect of antipsychotics or antidepressants